Multiple Effects of Ascorbic Acid against Chronic Diseases: Updated Evidence from Preclinical and Clinical Studies
Multiple Effects of Ascorbic Acid against Chronic Diseases: Updated Evidence from Preclinical and Clinical Studies
Abstract: severe disease commonly manifests as a systemic inflammatory process. Inflammation is Associated withthe enhanced production of reactive oxygen and nitrogen species and with a marked Reduction in the plasma concentrations of protective antioxidant molecules. This imbalance gives rise To oxidative stress, which is greater in patients with more severe conditions such as sepsis, cancer, Cardiovascular disease, acute respiratory distress syndrome, and burns. In these patients, oxidative
Stress can trigger cell, tissue, and organ damage, thus increasing morbidity and mortality. Ascorbic
Acid (asc) is a key nutrient thatserves as an antioxidant and a cofactor for numerous enzymatic Reactions. However, humans, unlike most mammals, are unable to synthesize it.
